Saturday, 23rd June 2018

2018.03.02 yolanda sanz


Prof. Yolanda Sanz

Instituto de Agroquímica y Tecnología de Alimentos, CSIC
Valencia, España





2018 03 02 Yolanda Sanz miniportYolanda Sanz is Research Professor at the Institute of Agrochemistry and Food Technology (IATA-CSIC, Valencia) and head of the research group on Microbial Ecology, Nutrition & Health at IATA-CSIC. She has carried out research activities in the Department of Molecular Microbiology and Immunology at University of Groningen (The Netherlands), at INRA in Jouy en Josas (France), at University of Verona (Italy), at Institute of Food Research (Reading, UK) and at Check Academy of Sciences (Check Republic). She is a member of the Panel on Dietetic Products, Nutrition and Allergies (NDA) of the European Food Safety Authority (EFSA) since 2009 and was Vice-Chair of the Panel from 2012 to 2015.

Her scientific field of interest is the human microbiome and its influence on nutritional and health status, with a focus on inflammatory, metabolic, neurodegenerative and behavioural disorders. She is also involved in research on probiotics and prebiotics.

Currently she coordinates the MyNewGut’s project, the largest European Union project on human microbiome with 30 partners. The project aims to determine the effect of the interactions between the gut microbiota, lifestyle and the genotype, in the risk of developing immunologic and metabolic diseases, and to develop new nutritional intervention strategies to prevent diet-­‐related diseases, such as obesity.



Selection of recent publications:

  • Agusti et al. 2017. Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice. Mol. Neurobiol. doi: 10.1007/s12035-017-0768-z.
  • Cenit et al. 2017. Influence of gut microbiota on neuropsychiatric disorders. World J. Gastroenterol. 23:5486-­‐5498.
  • Benítez-Páez et al. 2017. Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinION™ portable nanopore sequencer. Gigascience. 6:1-12.
  • Moya-Pérez et al. 2017. Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice. Brain Behav. Immun. 65:43-56.
  • Morris et al. 2016. The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease. Mol Neurobiol. 54:4432-4451.
  • Moratalla et al. 2016. Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis. J. Hepatol. 64:135-145.
  • Moratalla et al. 2016. Bifidobacterium pseudocatenulatum CECT7765 promotes a TLR2-dependent anti-inflammatory response in intestinal lymphocytes from mice with cirrhosis. Eur. J. Nutr. 55:197-206.
  • Galipeau et al. 2015. Intestinal microbiota modulates gluten-induced immunopathology in humanized mice. Am. J. Pathol. 185:2969-2982.
  • De Palma et al. 2015. Microbiota and host determinants of behavioural phenotype in maternally separated mice. Nat. Commun. 6:7735.
  • Olivares et al. 2015. The HLA-DQ2 genotype selects for early intestinal microbiota composition in infants at high risk of developing coeliac disease. Gut 64:406-417.
  • De Palma et al. 2014. Impaired responses to gliadin and gut microbes of immune cells from mice with altered stress-related behavior and premature immune senescence. J Neuroimmunol. 276:47-57.