{"id":278662,"date":"2024-05-27T14:28:03","date_gmt":"2024-05-27T12:28:03","guid":{"rendered":"https:\/\/dhcp205002.cbm.uam.es\/?page_id=278662"},"modified":"2026-02-23T18:19:41","modified_gmt":"2026-02-23T17:19:41","slug":"immune-system-development-and-function","status":"publish","type":"page","link":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/","title":{"rendered":"Immune system development and function"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#34609B&#8221; background_image=&#8221;https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/07\/iStock-1477214805small-scaled.jpg&#8221; background_position=&#8221;top_center&#8221; background_vertical_offset=&#8221;32%&#8221; min_height=&#8221;352px&#8221; height=&#8221;294px&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;4&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; custom_margin=&#8221;61px||||false|false&#8221; custom_padding=&#8221;||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(52,96,155,0.83)&#8221; custom_padding=&#8221;50px||50px|50px|false|false&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;0px||10px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Scientific program<\/p>\n<p>[\/et_pb_text][et_pb_heading title=&#8221;Interactions with the environment&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;Montserrat||||||||&#8221; title_text_color=&#8221;#FFFFFF&#8221; title_font_size=&#8221;43px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;157px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4 style=\"text-align: center;\"><span style=\"color: #13b5bd;\">UNITS IN THIS PROGRAM<br \/><\/span><\/h4>\n<hr \/>\n<h6 style=\"text-align: center;\"><span style=\"color: #abb8c3;\"><br \/><\/span>\u00a0 <span style=\"color: #13b5bd;\"><a href=\"\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/\">Immune system development and function<\/a> \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 <\/span><span style=\"color: #abb8c3;\"><a href=\"\/index.php\/scientific-programs\/interactions-with-the-environment\/microbes-in-health-and-welfare\/\">Microbes in health and welfare<\/a><\/span>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/h6>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; background_size=&#8221;custom&#8221; background_image_height=&#8221;84%&#8221; background_position=&#8221;bottom_right&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;<span style=%22color:#13B5BD%22>UNIT: <\/span>Immune system development and function&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe046;||divi||400&#8243; icon_color=&#8221;#13B5BD&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;26px&#8221; content_max_width=&#8221;1100px&#8221; content_max_width_tablet=&#8221;1100px&#8221; content_max_width_last_edited=&#8221;off|desktop&#8221; _builder_version=&#8221;4.27.0&#8243; header_level=&#8221;h1&#8243; header_font=&#8221;Montserrat||||||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;29px&#8221; header_line_height=&#8221;1.4em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;15px&#8221; body_line_height=&#8221;1.8em&#8221; image_icon_custom_margin=&#8221;6px||||false|false&#8221; background_layout=&#8221;dark&#8221; custom_margin=&#8221;50px||20px||false|false&#8221; custom_padding=&#8221;||14px||false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;right&#8221; animation_intensity_slide=&#8221;10%&#8221; animation=&#8221;off&#8221; image_max_width=&#8221;64px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;0px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(204,209,209,0.18)&#8221; custom_padding=&#8221;15px|15px|15px|15px|true|true&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Coordinator&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x57;||divi||400&#8243; icon_color=&#8221;#13B5BD&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;25px&#8221; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#34609B&#8221; image_icon_custom_margin=&#8221;-3px|-1px|||false|false&#8221; image_icon_custom_padding=&#8221;|0px|||false|false&#8221; custom_margin=&#8221;|-1px||0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_blurb][et_pb_blurb title=&#8221;Hisse van Santen&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/468.jpg&#8221; image_icon_width=&#8221;200px&#8221; module_class=&#8221;roundedImg&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;Montserrat|600|||||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#008C93&#8243; header_font_size=&#8221;18px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_blurb][et_pb_text _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-27px||||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"text-align: center;\">Lab 222<br \/>Ext. 4682<br \/>hvansanten(at)cbm.csic.es<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Research groups&#8221; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; title_level=&#8221;h2&#8243; title_text_align=&#8221;right&#8221; title_text_color=&#8221;#008C93&#8243; border_width_bottom=&#8221;2px&#8221; border_color_bottom=&#8221;#13B5BD&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_blurb title=&#8221;Signal transduction by the T-cell antigen receptor&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/signal-transmission-through-the-receptor-for-t-cell-antigen\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/16.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Balbino Alarc\u00f3n<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Immunity and viromics&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immunity-and-viromics\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/729.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Antonio Alcam\u00ed<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Cellular plasticity in development and cancer&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/cellular-plasticity-in-development-and-cancer\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/1191.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>C\u00e9sar Cobaleda<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Viral immunology&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/viral-immunology\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/601.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; 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icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Manuel Fresno<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Immunoregulatory mechanisms in the development of Chagas disease: translational applications&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/immunoregulatory-mechanisms-in-the-development-of-chagas-disease-translational-applications\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/117.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>N\u00faria Giron\u00e9s<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Nitric oxide and bioactive lipids signalling in the immune response&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/nitric-oxide-and-bioactive-lipids-signalling-in-the-immune-response\/&#8221; 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Navarro<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Metabolism in cancer and aging&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/metabolism-in-cancer-and-aging\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/5265.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Ana Ortega Molina<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Unconventional autophagy in health and disease&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/unconventional-autophagy-in-health-and-disease\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/5137.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Felipe X. Pimentel-Mui\u00f1os<\/p>\n<p>[\/et_pb_blurb][et_pb_divider color=&#8221;#AFDAF9&#8243; divider_style=&#8221;dotted&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.23.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;-5px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_blurb title=&#8221;Development of the human lymphohematopoietic system&#8221; url=&#8221;\/index.php\/scientific-programs\/interactions-with-the-environment\/immune-system-development-and-function\/development-of-the-human-lymphohematopoietic-system\/&#8221; image=&#8221;https:\/\/www.cbm.uam.es\/imgs\/127.jpg&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;200%&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#008C93&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; module_class=&#8221;roundedImg&#8221; 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