{"id":278951,"date":"2024-07-31T09:00:21","date_gmt":"2024-07-31T07:00:21","guid":{"rendered":"https:\/\/dhcp205002.cbm.uam.es\/?page_id=278951"},"modified":"2024-11-19T09:08:09","modified_gmt":"2024-11-19T08:08:09","slug":"tau-function-and-dysfunction-in-alzheimer-disease","status":"publish","type":"page","link":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/","title":{"rendered":"Tau function and dysfunction in Alzheimer disease"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.27.0″ _module_preset=”default” background_color=”#34609B” background_image=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/07\/iStock-1356994685small-scaled.jpg” background_position=”bottom_center” background_vertical_offset=”32%” min_height=”352px” height=”294px” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”2_5,3_5″ use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_margin=”61px||||false|false” custom_padding=”||0px|||” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(52,96,155,0.83)” custom_padding=”50px||50px|50px|false|false” border_radii=”on|15px|15px|15px|15px” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” text_text_color=”#FFFFFF” custom_margin=”0px||10px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”]<\/p>\n

Scientific Program<\/p>\n

[\/et_pb_text][et_pb_heading title=”Physiological and pathological processes” _builder_version=”4.25.0″ _module_preset=”default” title_font=”Montserrat||||||||” title_text_color=”#FFFFFF” title_font_size=”43px” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.23.4″ _module_preset=”default” custom_padding=”157px||||false|false” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

UNITS IN THIS PROGRAM
\n<\/span><\/h4>\n
\n

\nMolecular neuropathology<\/a><\/span>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Metabolic and signaling networks in disease<\/a><\/span><\/h6>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_enable_image=”off” background_size=”custom” background_image_height=”84%” background_position=”bottom_right” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”RESEARCH GROUP” _builder_version=”4.25.0″ _module_preset=”default” title_level=”h5″ title_text_color=”#13B5BD” custom_margin=”50px||0px||false|false” global_colors_info=”{}”][\/et_pb_heading][et_pb_blurb title=”Tau function and dysfunction in Alzheimer disease” use_icon=”on” font_icon=”||divi||400″ icon_color=”#13B5BD” icon_placement=”left” image_icon_width=”26px” content_max_width=”1100px” content_max_width_tablet=”1100px” content_max_width_last_edited=”off|desktop” _builder_version=”4.25.0″ header_level=”h1″ header_font=”Montserrat||||||||” header_text_color=”#000000″ header_font_size=”29px” header_line_height=”1.4em” body_font=”||||||||” body_font_size=”15px” body_line_height=”1.8em” image_icon_custom_margin=”6px||||false|false” background_layout=”dark” custom_margin=”|||” custom_padding=”||14px||false|false” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”10%” animation=”off” image_max_width=”64px” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(175,218,249,0.18)” custom_padding=”0px||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”\/imgs\/70.jpg” title_text=”logoRecurso 7″ align=”right” module_class=”roundedImg” _builder_version=”4.27.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Jes\u00fas \u00c1vila” _builder_version=”4.25.0″ _module_preset=”default” title_level=”h3″ title_text_align=”left” title_text_color=”#008C93″ global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”-27px||||false|false” link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

ORCID<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”\/imgs\/31.jpg” title_text=”logoRecurso 7″ align=”right” module_class=”roundedImg” _builder_version=”4.27.0″ _module_preset=”default” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”F\u00e9lix Hern\u00e1ndez” _builder_version=”4.25.0″ _module_preset=”default” title_level=”h3″ title_text_align=”left” title_text_color=”#008C93″ locked=”off” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”-27px||||false|false” link_option_url=”https:\/\/orcid.org\/0000-0001-7484-1150″ link_option_url_new_window=”on” locked=”off” global_colors_info=”{}”]ORCID<\/a>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”#13B5BD” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”#investiga” button_text=”Research” button_alignment=”center” _builder_version=”4.25.0″ _module_preset=”default” custom_button=”on” button_bg_color=”#34609B” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”#personal” button_text=”Group members” button_alignment=”center” _builder_version=”4.25.0″ _module_preset=”default” custom_button=”on” button_bg_color=”#34609B” custom_padding=”|44px||44px|false|true” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”#publica” button_text=”Publications” button_alignment=”center” _builder_version=”4.25.0″ _module_preset=”default” custom_button=”on” button_bg_color=”#34609B” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_enable_image=”off” background_size=”custom” background_image_height=”84%” background_position=”bottom_right” custom_margin=”0px||0px||false|false” custom_padding=”0px||15px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.23.4″ _module_preset=”default” custom_margin=”20px||||false|false” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”resumen” module_id=”resumen” module_class=”resumen” _builder_version=”4.27.3″ _module_preset=”default” text_font_size=”15px” text_line_height=”1.8em” background_color=”#f1f8fe” custom_padding=”20px|20px|20px|20px|true|false” border_width_top=”1px” border_color_top=”#008C93″ border_width_bottom=”1px” border_color_bottom=”#008C93″ global_colors_info=”{}”]<\/p>\n

To understand the mechanisms of tau pathology in neurodegenerative processes, such as Alzheimer’s disease, with the goal of preventing their development<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.4″ _module_preset=”default” custom_padding=”||||false|false” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Figura_JAvila.jpg” title_text=”Imagen representativa” _builder_version=”4.27.3″ _module_preset=”default” width=”49%” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.23.4″ _module_preset=”default” custom_margin=”||||false|false” custom_padding=”0px||||false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Research” module_id=”investiga” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.3″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Tau is a neuronal protein that plays a direct or indirect role in various neuronal functions. Dysfunctions in tau can lead to neurodegenerative disorders, known as tauopathies, with Alzheimer\u2019s disease being the most significant. Tau\u2019s functions are influenced by its subcellular localization and its binding to specific neuronal components. Our objective is to analyze these known tau functions and explore potential new ones.<\/p>\n

We have examined the structural and functional differences between human and mouse tau proteins, focusing on an extra amino acid sequence unique to human tau, which plays a role in axonal transport of certain proteins. Additionally, we have studied the mechanism responsible for extracellular tau secretion and tau\u2019s involvement in localizing NMDA extrasynaptic receptors. Given that tau is a phosphoprotein primarily modified by the GSK3\u03b2 kinase, we have also investigated the effects of GSK3\u03b2 overexpression in neuronal cells. In Dr. Hern\u00e1ndez\u2019s group, we analyzed tau\u2019s presence in glial cells (oligodendrocytes, astrocytes, and microglia) and discovered that various cell surface receptors may facilitate interactions between extracellular tau and neurons or glial cells.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Jesus-Avila-Grupo-Fotografo-Alvaro-Munoz-Guman_16-1-scaled.jpg” title_text=”Jesu\u0301s-A\u0301vila-Grupo” _builder_version=”4.27.3″ _module_preset=”default” custom_margin=”60px||||false|false” custom_padding=”|||27px||” animation_style=”zoom” border_width_all=”3px” border_color_all=”#13B5BD” box_shadow_style=”preset3″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” custom_padding=”0px||||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.3″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Our group has collaborated extensively with other research teams, both within and outside of the CBM, on topics related to Alzheimer\u2019s disease, other neurodegenerative disorders, and aging. Regarding aging, we have documented the rejuvenation of certain aged granule neurons in the hippocampal region following expression of reprogramming (Yamanaka) factors.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(0,0,0,0.04)” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Group members” module_id=”personal” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.25.0″ _module_preset=”default” max_width=”2560px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_code _builder_version=”4.25.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=\"4.25.0\" _module_preset=\"default\" column_structure=\"1_4,1_4,1_4,1_4\" hover_enabled=\"0\" sticky_enabled=\"0\"][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"F\u00e9lix Hern\u00e1ndez P\u00e9rez\" image=\"\/imgs\/31.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4563
fhernandez(at)cbm.csic.es<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Jes\u00fas \u00c1vila de Grado\" image=\"\/imgs\/70.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4564
javila(at)cbm.csic.es<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Raquel Cuadros Catal\u00e1n\" image=\"\/imgs\/213.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
rcuadros(at)cbm.csic.es<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Vega Garc\u00eda-Escudero Barreras\" image=\"\/imgs\/231.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
vescudero(at)cbm.csic.es<\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.25.0\" _module_preset=\"default\" column_structure=\"1_4,1_4,1_4,1_4\" hover_enabled=\"0\" sticky_enabled=\"0\"][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Nuria de la Torre Alonso\" image=\"\/imgs\/877.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4803
ndelatorre(at)cbm.csic.es<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Mar\u00eda Jos\u00e9 P\u00e9rez Alvarez\" image=\"\/imgs\/default.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Paula Ram\u00edrez Mallavibarrena\" image=\"\/imgs\/default.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Indalo Domene Serrano\" image=\"\/imgs\/5740.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
<\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.25.0\" _module_preset=\"default\" column_structure=\"1_4,1_4,1_4,1_4\" hover_enabled=\"0\" sticky_enabled=\"0\"][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Francisco Vallejo Bedia\" image=\"\/imgs\/5751.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 9542
<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Irene Olivares Raya\" image=\"\/imgs\/default.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Blanca P\u00e9rez Quiroga\" image=\"\/imgs\/default.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4592
<\/p>[\/et_pb_blurb][\/et_pb_column][et_pb_column _builder_version=\"4.25.0\" _module_preset=\"default\" type=\"1_4\"][et_pb_blurb title=\"Loredana Barone \" image=\"\/imgs\/default.jpg\" _builder_version=\"4.25.0\" _module_preset=\"default\" header_text_align=\"center\" body_text_align=\"center\" global_colors_info=\"{}\" theme_builder_area=\"post_content\" module_class=\"roundedImg\"]

Lab.: 208 Ext.: 4564
<\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Selected publications” module_id=”personal” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.23.4″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”data:image\/svg+xml;base64,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” title_text=”Captura de Pantalla 2024-05-28 a las 1.22.50″ url_new_window=”on” _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” link_option_url=”https:\/\/www.pnas.org\/doi\/10.1073\/pnas.81.19.5989?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed” link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly.<\/h3>\n

L Serrano et al.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/06\/Figure2_embj7593509-fig-0001-m-J.-AVILA-Lab-1.jpg” title_text=” ” url_new_window=”on” _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” link_option_url=”https:\/\/www.embopress.org\/doi\/full\/10.1093\/emboj\/20.1.27″ link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

Decreased nuclear \u03b2\u2010catenin, tau hyperphosphorylation and neurodegeneration in GSK\u20103\u03b2 conditional transgenic mice<\/h3>\n

Jos\u00e9 J. Lucas et al.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.23.4″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/06\/Figure3_41380_2013_Article_BFmp20134_Fig5_HTML-J.-AVILA-Lab-1.webp” title_text=” ” url_new_window=”on” _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” link_option_url=”https:\/\/www.nature.com\/articles\/mp20134″ link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

GSK-3\u03b2 overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons\u00a0in vivo<\/h3>\n

M Llorens-Mart\u00edn et al.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/06\/Figure4_401_2021_2317_Fig4_HTML-J.-AVILA-Lab-1.png” title_text=” ” url_new_window=”on” _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}” src__hover_enabled=”off|desktop”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” link_option_url=”https:\/\/link.springer.com\/article\/10.1007\/s00401-021-02317-z” link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer\u2019s disease<\/h3>\n

Vega Garc\u00eda-Escudero et al.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(0,0,0,0.04)” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Latest publications” module_id=”publica” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_code _builder_version=”4.25.2″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Cargando publicaciones…<\/div>\n

[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”#34609B” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Scientific Programs” _builder_version=”4.25.0″ _module_preset=”default” title_text_color=”#FFFFFF” title_font_size=”26px” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”||||false|false” custom_padding=”0px|0px|0px|0px|false|true” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects1_sf.png” title_text=” ” url=”\/index.php\/scientific-programs\/genome-dynamics-and-function\/” _builder_version=”4.25.2″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects2_sf.png” title_text=” ” url=”\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/” _builder_version=”4.25.2″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects3_sf.png” title_text=” ” url=”\/index.php\/scientific-programs\/physiological-and-pathological-processes\/” _builder_version=”4.25.2″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects4_sf.png” title_text=” ” url=”\/index.php\/scientific-programs\/interactions-with-the-environment\/” _builder_version=”4.25.2″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Scientific ProgramUNITS IN THIS PROGRAM Molecular neuropathology\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Metabolic and signaling networks in diseaseORCIDORCIDTo understand the mechanisms of tau pathology in neurodegenerative processes, such as Alzheimer’s disease, […]<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":278654,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-278951","page","type-page","status-publish","hentry"],"yoast_head":"\nTau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa\" \/>\n<meta property=\"og:description\" content=\"Scientific ProgramUNITS IN THIS PROGRAM Molecular neuropathology\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Metabolic and signaling networks in diseaseORCIDORCIDTo understand the mechanisms of tau pathology in neurodegenerative processes, such as Alzheimer's disease, […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Centro de Biolog\u00eda Molecular Severo Ochoa\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-19T08:08:09+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/\",\"url\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/\",\"name\":\"Tau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa\",\"isPartOf\":{\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#website\"},\"datePublished\":\"2024-07-31T07:00:21+00:00\",\"dateModified\":\"2024-11-19T08:08:09+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/www.cbm.uam.es\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Scientific programs\",\"item\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Physiological and pathological processes\",\"item\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Molecular neuropathology\",\"item\":\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Tau function and dysfunction in Alzheimer disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#website\",\"url\":\"https:\/\/www.cbm.uam.es\/?lang=es\/\",\"name\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\",\"description\":\"Official website of the CBM, CSIC - UAM. Biomedical research centre.\",\"publisher\":{\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.cbm.uam.es\/?lang=es\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#organization\",\"name\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\",\"url\":\"https:\/\/www.cbm.uam.es\/?lang=es\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png\",\"contentUrl\":\"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png\",\"width\":800,\"height\":342,\"caption\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\"},\"image\":{\"@id\":\"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/","og_locale":"en_US","og_type":"article","og_title":"Tau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa","og_description":"Scientific ProgramUNITS IN THIS PROGRAM Molecular neuropathology\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Metabolic and signaling networks in diseaseORCIDORCIDTo understand the mechanisms of tau pathology in neurodegenerative processes, such as Alzheimer's disease, […]","og_url":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/","og_site_name":"Centro de Biolog\u00eda Molecular Severo Ochoa","article_modified_time":"2024-11-19T08:08:09+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/","url":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/","name":"Tau function and dysfunction in Alzheimer disease - Centro de Biolog\u00eda Molecular Severo Ochoa","isPartOf":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#website"},"datePublished":"2024-07-31T07:00:21+00:00","dateModified":"2024-11-19T08:08:09+00:00","breadcrumb":{"@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/tau-function-and-dysfunction-in-alzheimer-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/www.cbm.uam.es\/"},{"@type":"ListItem","position":2,"name":"Scientific programs","item":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/"},{"@type":"ListItem","position":3,"name":"Physiological and pathological processes","item":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/"},{"@type":"ListItem","position":4,"name":"Molecular neuropathology","item":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/physiological-and-pathological-processes\/molecular-neuropathology\/"},{"@type":"ListItem","position":5,"name":"Tau function and dysfunction in Alzheimer disease"}]},{"@type":"WebSite","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#website","url":"https:\/\/www.cbm.uam.es\/?lang=es\/","name":"Centro de Biolog\u00eda Molecular Severo Ochoa","description":"Official website of the CBM, CSIC - UAM. Biomedical research centre.","publisher":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.cbm.uam.es\/?lang=es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#organization","name":"Centro de Biolog\u00eda Molecular Severo Ochoa","url":"https:\/\/www.cbm.uam.es\/?lang=es\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/","url":"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png","contentUrl":"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png","width":800,"height":342,"caption":"Centro de Biolog\u00eda Molecular Severo Ochoa"},"image":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/278951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/comments?post=278951"}],"version-history":[{"count":0,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/278951\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/278654"}],"wp:attachment":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/media?parent=278951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}