{"id":293644,"date":"2026-01-23T09:02:51","date_gmt":"2026-01-23T08:02:51","guid":{"rendered":"https:\/\/www.cbm.uam.es\/?page_id=293644"},"modified":"2026-01-23T09:02:51","modified_gmt":"2026-01-23T08:02:51","slug":"morfogenesis-del-sistema-nervioso-central-de-drosophila","status":"publish","type":"page","link":"https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/homeostasis-de-tejidos-y-organos\/arquitectura-celular-y-organogenesis\/morfogenesis-del-sistema-nervioso-central-de-drosophila\/?lang=es","title":{"rendered":"Morfog\u00e9nesis del sistema nervioso central de Drosophila"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.27.5″ _module_preset=”default” background_color=”#34609B” background_image=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/07\/iStock-1284442724small-scaled.jpg” background_position=”bottom_center” background_vertical_offset=”32%” min_height=”352px” height=”294px” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”2_5,3_5″ use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_margin=”61px||||false|false” custom_padding=”||0px|||” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(52,96,155,0.83)” custom_padding=”50px||50px|50px|false|false” border_radii=”on|15px|15px|15px|15px” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” text_text_color=”#FFFFFF” custom_margin=”0px||10px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”]<\/p>\n

Programa Cient\u00edfico<\/p>\n

[\/et_pb_text][et_pb_heading title=”Homeostasis de tejidos y \u00f3rganos” _builder_version=”4.27.5″ _module_preset=”default” title_font=”Montserrat||||||||” title_text_color=”#FFFFFF” title_font_size=”43px” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.23.4″ _module_preset=”default” custom_padding=”157px||||false|false” global_colors_info=”{}”][et_pb_text _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

UNIDADES EN ESTE PROGRAMA
\n<\/span><\/h4>\n
\n

\nArquitectura celular y organog\u00e9nesis <\/a><\/span> Comunicaci\u00f3n intercelular e inflamaci\u00f3n<\/a><\/span><\/h6>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_enable_image=”off” background_size=”custom” background_image_height=”84%” background_position=”bottom_right” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”IP JUNIOR” _builder_version=”4.27.5″ _module_preset=”default” title_level=”h5″ title_text_color=”#13B5BD” custom_margin=”50px||0px||false|false” global_colors_info=”{}”][\/et_pb_heading][et_pb_blurb title=”Morfog\u00e9nesis del sistema nervioso central de Drosophila” use_icon=”on” font_icon=”||divi||400″ icon_color=”#13B5BD” icon_placement=”left” image_icon_width=”26px” content_max_width=”1100px” content_max_width_tablet=”1100px” content_max_width_last_edited=”off|desktop” _builder_version=”4.27.5″ header_level=”h1″ header_font=”Montserrat||||||||” header_text_color=”#000000″ header_font_size=”29px” header_line_height=”1.4em” body_font=”||||||||” body_font_size=”15px” body_line_height=”1.8em” image_icon_custom_margin=”6px||||false|false” background_layout=”dark” custom_margin=”|||” custom_padding=”||14px||false|false” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”10%” animation=”off” image_max_width=”64px” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(175,218,249,0.18)” custom_padding=”0px||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_4,3_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2025\/07\/persona.png” title_text=”persona” align=”right” module_class=”roundedImg” _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Katerina Karkali” _builder_version=”4.27.5″ _module_preset=”default” title_level=”h3″ title_text_align=”left” title_text_color=”#008C93″ global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”#13B5BD” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_enable_image=”off” background_size=”custom” background_image_height=”84%” background_position=”bottom_right” custom_margin=”0px||0px||false|false” custom_padding=”0px||15px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.27.5″ _module_preset=”default” custom_margin=”40px||||false|false” custom_padding=”20px||||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Investigaci\u00f3n” module_id=”investiga” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

El comportamiento animal est\u00e1 determinado por la integraci\u00f3n de est\u00edmulos interoceptivos y exteroceptivos mediados por los circuitos neuronales del sistema nervioso central (SNC). Aunque actualmente se est\u00e1 dedicando un esfuerzo considerable a descifrar los conectomas de diferentes organismos, la contribuci\u00f3n de la organizaci\u00f3n estructural de los tejidos a su capacidad integradora ha sido relativamente poco estudiada. En este contexto, las redes gliales y la matriz extracelular (MEC) forman conjuntamente una unidad estructural din\u00e1mica e interdependiente que configura el SNC. <\/p>\n

Como investigador Ram\u00f3n y Cajal en el CBM, estudio c\u00f3mo la interacci\u00f3n din\u00e1mica entre la gl\u00eda y la MEC durante el desarrollo contribuye a la morfog\u00e9nesis y la funci\u00f3n del SNC. Para abordar esta cuesti\u00f3n, utilizo el SNC embrionario de Drosophila<\/em> como sistema modelo, centr\u00e1ndome en la condensaci\u00f3n del cord\u00f3n nervioso ventral (VNC). A mitad de la embriog\u00e9nesis, y simult\u00e1neamente al ensamblaje de los circuitos neuronales en una serie de m\u00f3dulos neuronales interconectados, el VNC sufre una condensaci\u00f3n dram\u00e1tica asociada con el inicio de la coordinaci\u00f3n motora y la eclosi\u00f3n del embri\u00f3n. La condensaci\u00f3n del VNC representa un modelo novedoso para investigar la relaci\u00f3n entre estructura y funci\u00f3n, ya que es muy sensible a los cambios arquitect\u00f3nicos y est\u00e1 vinculada a un resultado conductual claro: la capacidad del embri\u00f3n para realizar peristaltismo y eclosionar con \u00e9xito. <\/p>\n

Empleando la segmentaci\u00f3n de tejidos en 3D basada en FIB-SEM, microscop\u00eda confocal de alta resoluci\u00f3n y t\u00e9cnicas avanzadas de procesamiento de im\u00e1genes, persigo dos objetivos principales:<\/p>\n

1. Examinar c\u00f3mo se ensamblan las redes de gl\u00eda e interact\u00faan din\u00e1micamente con la MEC durante el desarrollo del SNC.<\/p>\n

2. Evaluar c\u00f3mo las propiedades materiales de la gl\u00eda y la MEC influyen en el equilibrio mec\u00e1nico del tejido y afectan al funcionamiento de los circuitos neuronales.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”rgba(0,0,0,0.04)” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Publicaciones representativas” module_id=”personal” _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”0px|||0px|false|false” custom_padding=”3px|||8px|false|false” border_width_left=”6px” border_color_left=”#34609B” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.23.4″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2026\/01\/pub-1.jpg” title_text=”pub 1″ url=”https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1534580722001678?via%3Dihub” url_new_window=”on” _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” link_option_url=”https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1534580722001678?via%3Dihub” link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

Condensation of the Drosophila<\/em> nerve cord is oscillatory and depends on coordinated mechanical interactions<\/h3>\n

Karkali, K. et al.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2026\/01\/pub-2.png” title_text=”pub 2″ url=”https:\/\/www.nature.com\/articles\/s41467-023-36388-1″ url_new_window=”on” _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” link_option_url=”https:\/\/www.nature.com\/articles\/s41467-023-36388-1″ link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila <\/em>embryos<\/h3>\n

Karkali, K. et al<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.23.4″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2026\/01\/pub-3.png” title_text=”pub 3″ url=”https:\/\/www.nature.com\/articles\/s41467-023-43783-1″ url_new_window=”on” _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” link_option_url=”https:\/\/www.nature.com\/articles\/s41467-023-43783-1″ link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

Puckered and JNK signaling in pioneer neurons coordinate the motor activity of the Drosophila<\/em> embryo<\/h3>\n

Karkali, K. et al<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2026\/01\/pub-4.jpg” title_text=”pub 4″ url=”https:\/\/www.sciencedirect.com\/science\/article\/pii\/S266616672200781X?via%3Dihub” url_new_window=”on” _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” link_option_url=”https:\/\/www.sciencedirect.com\/science\/article\/pii\/S266616672200781X?via%3Dihub” link_option_url_new_window=”on” global_colors_info=”{}”]<\/p>\n

Measuring ventral nerve cord stiffness in live flat-dissected Drosophila<\/em> embryos by atomic force microscopy<\/h3>\n

Karkali, K. et al<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.4″ _module_preset=”default” background_color=”#34609B” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Programas cient\u00edficos” _builder_version=”4.25.0″ _module_preset=”default” title_text_color=”#FFFFFF” title_font_size=”26px” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.25.0″ _module_preset=”default” custom_margin=”||||false|false” custom_padding=”0px|0px|0px|0px|false|true” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects1_sf.png” title_text=”areas_proyects1_sf” url=”https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/dinamica-y-funcion-del-genoma\/?lang=es” _builder_version=”4.25.0″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects2_sf.png” title_text=”areas_proyects2_sf” url=”https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/homeostasis-de-tejidos-y-organos\/?lang=es” _builder_version=”4.25.0″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects3_sf.png” title_text=”areas_proyects3_sf” url=”https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/procesos-fisiologicos-y-patologicos\/?lang=es” _builder_version=”4.25.0″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.23.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/05\/areas_proyects4_sf.png” title_text=”areas_proyects4_sf” url=”https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/interacciones-con-el-entorno\/?lang=es” _builder_version=”4.25.0″ _module_preset=”default” animation_style=”zoom” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Programa Cient\u00edficoUNIDADES EN ESTE PROGRAMA Arquitectura celular y organog\u00e9nesis Comunicaci\u00f3n intercelular e inflamaci\u00f3nEl comportamiento animal est\u00e1 determinado por la integraci\u00f3n de est\u00edmulos interoceptivos y exteroceptivos mediados por los circuitos neuronales […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":283187,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-293644","page","type-page","status-publish","hentry"],"yoast_head":"\nMorfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Morfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa\" \/>\n<meta property=\"og:description\" content=\"Programa Cient\u00edficoUNIDADES EN ESTE PROGRAMA Arquitectura celular y organog\u00e9nesis Comunicaci\u00f3n intercelular e inflamaci\u00f3nEl comportamiento animal est\u00e1 determinado por la integraci\u00f3n de est\u00edmulos interoceptivos y exteroceptivos mediados por los circuitos neuronales […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/\" \/>\n<meta property=\"og:site_name\" content=\"Centro de Biolog\u00eda Molecular Severo Ochoa\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"12 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/scientific-programs\\\/tissue-and-organ-homeostasis\\\/cell-architecture-and-organogenesis\\\/drosophila-central-nervous-system-morphogenesis\\\/\",\"url\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/scientific-programs\\\/tissue-and-organ-homeostasis\\\/cell-architecture-and-organogenesis\\\/drosophila-central-nervous-system-morphogenesis\\\/\",\"name\":\"Morfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#website\"},\"datePublished\":\"2026-01-23T08:02:51+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/scientific-programs\\\/tissue-and-organ-homeostasis\\\/cell-architecture-and-organogenesis\\\/drosophila-central-nervous-system-morphogenesis\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/scientific-programs\\\/tissue-and-organ-homeostasis\\\/cell-architecture-and-organogenesis\\\/drosophila-central-nervous-system-morphogenesis\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/scientific-programs\\\/tissue-and-organ-homeostasis\\\/cell-architecture-and-organogenesis\\\/drosophila-central-nervous-system-morphogenesis\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\\\/\\\/www.cbm.uam.es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Programas Cient\u00edficos\",\"item\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/programas-cientificos\\\/?lang=es\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Homeostasis de tejidos y \u00f3rganos\",\"item\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/programas-cientificos\\\/homeostasis-de-tejidos-y-organos\\\/?lang=es\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Arquitectura celular y organog\u00e9nesis\",\"item\":\"https:\\\/\\\/www.cbm.uam.es\\\/index.php\\\/programas-cientificos\\\/homeostasis-de-tejidos-y-organos\\\/arquitectura-celular-y-organogenesis\\\/?lang=es\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Morfog\u00e9nesis del sistema nervioso central de Drosophila\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#website\",\"url\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/\",\"name\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\",\"description\":\"Official website of the CBM, CSIC - UAM. Biomedical research centre.\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#organization\",\"name\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\",\"url\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.cbm.uam.es\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/Logo-CBM-color-fondo-transparente.png\",\"contentUrl\":\"https:\\\/\\\/www.cbm.uam.es\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/Logo-CBM-color-fondo-transparente.png\",\"width\":800,\"height\":342,\"caption\":\"Centro de Biolog\u00eda Molecular Severo Ochoa\"},\"image\":{\"@id\":\"https:\\\/\\\/www.cbm.uam.es\\\/?lang=es\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Morfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/","og_locale":"en_US","og_type":"article","og_title":"Morfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa","og_description":"Programa Cient\u00edficoUNIDADES EN ESTE PROGRAMA Arquitectura celular y organog\u00e9nesis Comunicaci\u00f3n intercelular e inflamaci\u00f3nEl comportamiento animal est\u00e1 determinado por la integraci\u00f3n de est\u00edmulos interoceptivos y exteroceptivos mediados por los circuitos neuronales […]","og_url":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/","og_site_name":"Centro de Biolog\u00eda Molecular Severo Ochoa","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"12 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/","url":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/","name":"Morfog\u00e9nesis del sistema nervioso central de Drosophila - Centro de Biolog\u00eda Molecular Severo Ochoa","isPartOf":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#website"},"datePublished":"2026-01-23T08:02:51+00:00","breadcrumb":{"@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.cbm.uam.es\/index.php\/scientific-programs\/tissue-and-organ-homeostasis\/cell-architecture-and-organogenesis\/drosophila-central-nervous-system-morphogenesis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/www.cbm.uam.es\/"},{"@type":"ListItem","position":2,"name":"Programas Cient\u00edficos","item":"https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/?lang=es"},{"@type":"ListItem","position":3,"name":"Homeostasis de tejidos y \u00f3rganos","item":"https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/homeostasis-de-tejidos-y-organos\/?lang=es"},{"@type":"ListItem","position":4,"name":"Arquitectura celular y organog\u00e9nesis","item":"https:\/\/www.cbm.uam.es\/index.php\/programas-cientificos\/homeostasis-de-tejidos-y-organos\/arquitectura-celular-y-organogenesis\/?lang=es"},{"@type":"ListItem","position":5,"name":"Morfog\u00e9nesis del sistema nervioso central de Drosophila"}]},{"@type":"WebSite","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#website","url":"https:\/\/www.cbm.uam.es\/?lang=es\/","name":"Centro de Biolog\u00eda Molecular Severo Ochoa","description":"Official website of the CBM, CSIC - UAM. Biomedical research centre.","publisher":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.cbm.uam.es\/?lang=es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#organization","name":"Centro de Biolog\u00eda Molecular Severo Ochoa","url":"https:\/\/www.cbm.uam.es\/?lang=es\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/","url":"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png","contentUrl":"https:\/\/www.cbm.uam.es\/wp-content\/uploads\/2024\/11\/Logo-CBM-color-fondo-transparente.png","width":800,"height":342,"caption":"Centro de Biolog\u00eda Molecular Severo Ochoa"},"image":{"@id":"https:\/\/www.cbm.uam.es\/?lang=es\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/293644","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/comments?post=293644"}],"version-history":[{"count":2,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/293644\/revisions"}],"predecessor-version":[{"id":293646,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/293644\/revisions\/293646"}],"up":[{"embeddable":true,"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/pages\/283187"}],"wp:attachment":[{"href":"https:\/\/www.cbm.uam.es\/index.php\/wp-json\/wp\/v2\/media?parent=293644"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}