Monday, 24th April 2017
Inside the Cell
Special Seminar 25/04/2017
Flavia Caridi / Elena Moreno: Bases moleculares de la estabilidad de la cápsida de los aftovirus / Capacidad adaptativa del virus de la fiebre aftosa y nuevas opciones terapéuticas
Special Seminar 26/04/2017
Raoul CM Hennekam: Next generation sequencing demands next generation phenotyping
Special Seminar 27/04/2017
Hrvoje Šikić: Stochastic Model of Eye Lens Growth
Advances in Biomedicine Seminar Cycle 28/04/2017
Anja Groth: Chromatin Replication and Epigenome Maintenance
18th Severo Ochoa Seminar Cycle 12/05/2017
Prof. Sandrine Bourdoulous: Vascular colonization by Neisseria meningitidis: dissecting the host/pathogen interaction networks
The CBMSO joins the celebration of International Women's and Girls' Day in Science. The CBMSO has a staff of 545 workers, of which 320 are women
EMBO Workshop on Antigen Processing and Presentation 28 - 31 May 2017
International RTs Symposium 2017
Río Tinto, fundamental and applied aspects of a terrestrial Mars analogue
Convenio entre RedELA, Red de enfermos de esclerosis lateral amiotrófica (ELA), la Fundación Severo Ochoa y el grupo de investigación del Dr. Luis Carrasco para continuar con el estudio sobre la etiología de la ELA
CBMSO announces its participation in the European project METAFLUIDICS
Convenio de colaboración entre el CBMSO y la Fundación SEUR para promover el proyecto TAPONES PARA UNA NUEVA VIDA
ENDOCORNEA. Convenio de Colaboración entre el Instituto de Investigaciones Sanitarias de la Fundación Jiménez Díaz y el CSIC para investigar en el CBMSO la respuesta inflamatoria del endotelio de córnea humana y su relación con patologías oculares
Short videos
Answers to eight essential questions about our cells
Convenio de colaboración entre la Fundación Severo Ochoa y la Fundación Isabel Gemio para promover la investigación de enfermedades metabólicas hereditarias
Aims to explore question is whether developmental mechanisms can help to maintain adult organ homeostasis and their relationship with disease
Ultrahigh-throughput platform for the screening of thermostable proteins by thermophillic in vitro transcription-translation and microfluidics
A new human primase/polymerase with a potential impact in aging
Redes moleculares y celulares en enfermedades inflamatorias
Host Microbe Interactions in Health and Disease: Interface with the Immune System
European Consortium for Development of Stem Cell-Based Therapy for Thymic Regeneration
The study of the biology of neural stem cells for its use in cell therapy of neurodegenerative diseases
Spanish cell therapy network



In the CBMSO we focus our research on the study of the molecular basis of human diseases with the ultimate goal of providing the necessary knowledge to design therapies, procedures and diagnostic methods that help improve the quality and life expectancy.

Our research in molecular biomedicine is based on two realities:

  • the need to reduce the social impact of the most disabling diseases.
  • the need to understand the molecular mechanisms of diseases to be able to translate them into biomedical applications.

Featured News

Descubierto un nuevo mecanismo para contrarrestar los efectos de la obesidad y la resistencia a insulina
  • La inhibición de una proteína implicada tanto en la señalización de la insulina como en la adrenérgica puede mejorar trastornos metabólicos
  • Inhibir GRK2 puede limitar las consecuencias negativas de la obesidad y otros trastornos asociados

Representative Publications

Recent Publications

pdf flat small Human PrimPol activity is enhanced by RPA

pdf flat small Mutualism supports biodiversity when the direct competition is weak

pdf flat small Discovery of a new family of relaxases in Firmicutes bacteria

pdf flat small N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes

pdf flat small Altered bone marrow lymphopoiesis and interleukin-6-dependent inhibition of thymocyte differentiation contribute to thymic atrophy during Trypanosoma cruzi infection

pdf flat small PLD3 gene and processing of APP

pdf flat small Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning

pdf flat small Characterization of two distinct early post-entry blocks to HIV-1 in common marmoset lymphocytes

pdf flat small Fungal Enolase, β-Tubulin, and Chitin Are Detected in Brain Tissue from Alzheimer’s Disease Patients

pdf flat small G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis

pdf flat small Effective competition determines the global stability of model ecosystems

pdf flat small Genomic cartography and proposal of nomenclature for the repeated, interspersed elements of the Leishmania major SIDER2 family and identification of SIDER2-containing transcripts

pdf flat small Learning structural bioinformatics and evolution with a snake puzzle

pdf flat small TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol

pdf flat small Short-Term Grafting of Human Neural Stem Cells: Electrophysiological Properties and Motor Behavioral Amelioration in Experimental Parkinson’s Disease

pdf flat small Proteins: bridging theory and experiment

pdf flat small Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels

pdf flat small Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development

pdf flat small Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

pdf flat small New mutations for nodal lymphomas of TFH origin

pdf flat small ProtASR: An Evolutionary Framework for Ancestral Protein Reconstruction with Selection on Folding Stability

pdf flat small Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

pdf flat small Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated apoptosis

pdf flat small What evolution tells us about protein physics, and protein physics tells us about evolution


Scientific Report


Nicolás Cabrera, 1, 28049 Madrid
Tel.: +34-911964401
Fax: +34-911964420
institucional at