Website CBM_CSIC_UAM Centro de Biología Molecular Severo Ochoa
Decoding life
PRINCIPAL INVESTIGATOR: José Antonio Tercero
SCIENTIFIC PROGRAM: Genome dynamics and function
JOB OFFER: Postdoctoral position
PROJECT TITLE: Mechanisms of genome integrity maintenance
Project description
The general goal of this project is to contribute to the understanding of the mechanisms involved in preventing genomic instability, a hallmark of cancer and other diseases and a feature of premature aging and developmental abnormalities. A major cause of genome instability is the presence of unrepaired DNA damage, and the project will mainly address the study of how DNA damage tolerance pathways contribute to maintaining genome integrity in proliferating cells and how these are interconnected with proteostasis networks. The project will combine in vivo and in vitro studies and the methodology will include molecular biology, cellular biology, genetics and biochemistry techniques. Fundamental biological processes are evolutionarily conserved, and the yeast Saccharomyces cerevisiae will be used as a working eukaryotic model.
Duration
2 years
Requirements
Candidates must hold a PhD in Molecular Biology, Genetics, Biotechnology, Microbiology or related fields.
Contact
jatercero@cbm.csic.es. Ph.: +34 91 1964818
Other information
Type of contract: CSIC M3 group contract.
Application deadline: 15 September
Starting date: available from September 2025, but flexible.
Interested applicants should submit their full CV, a motivation letter and the names and contact details of minimum two references to jatercero@cbm.csic.es as soon as possible.
To apply for this job email your details to jatercero@cbm.csic.es