Unconventional autophagy in health and disease

Our research group is looking for candidates to apply for postdoctoral contracts offered by the Spanish Government (Juan de la Cierva Program, deadline 15/11/2025) and/or Fundación La Caixa (Junior Leader call, Incoming and Retaining modalities, deadline 15/09/2025).

The target lab is directed by Dr. Felipe X. Pimentel-Muiños. We study how unconventional autophagic processes are involved in human health and disease, with a focus on inflammatory pathologies and cancer (https://www.cbm.uam.es/fxpimentel).

Interested candidates with a PhD in biosciences and a competitive publication record should send their CV, a motivation letter and the contact information of 2 references to the Principal Investigator (fxp@cbm.csic.es ).

Selected Publications:

1.      Terraza-Silvestre, E., et al. An unconventional autophagic pathway that inhibits ATP secretion during apoptosis. Nat. Commun., 16:3409 (2025)

2.      Serramito-Gómez, I., et al. Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain. Nat. Commun., 11:5919 (2020)

3.      Slowicka, K., et al. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nat. Commun., 10:1834 (2019)

4.      Boada-Romero, E., et al. The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nat. Commun, 7:11821 (2016)

5.      Boada-Romero, E., et al. TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3. EMBO J., 32:566-582 (2013)